Search results for "Poly ethylene glycol"

showing 5 items of 5 documents

Ester Functional Epoxide Monomers for Random and Gradient Poly(ethylene glycol) Polyelectrolytes with Multiple Carboxylic Acid Moieties

2020

The tailormade ester functional epoxides, methyl 4,5-epoxypentenoate (MEP) and tbutyl 4,5-epoxypentenoate (tBEP), were synthesized in good overall yields (60–65%) in short reaction sequences. Both ...

Inorganic Chemistrychemistry.chemical_classificationchemistry.chemical_compoundPoly ethylene glycolMonomerPolymers and PlasticschemistryCarboxylic acidOrganic ChemistryPolymer chemistryMaterials ChemistryEpoxidePolyelectrolyteMacromolecules
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Collapsibility of metastable sand by non-conventional oedometer tests

2018

The stability of foundations soils could represent a clear and present threat for the conservation of even well preserved buildings, particularly for Architectural heritage conservation and land art heritage. A dramatic case is the presence of collapsible metastable sands as foundation soils, as it occurs in the sacral complex Valle dei Templi in Agrigento. This site listed by UNESCO, stands on a crest of a calcarenite cuesta, overlaying a layer of these sands. When the collapsible sand is dry, the structure is strong enough to bond the sand particles together. When the sand becomes wet, a de-structuration mechanism occurs and the soil’s strength is compromised. This paper has a twofold aim…

Poly ethylene glycol0211 other engineering and technologiesGeneral Physics and Astronomy02 engineering and technology01 natural sciencesPhysics and Astronomy (all)Architectural heritageCollapse potentialMetastability0103 physical sciencesGeneral Materials ScienceGeotechnical engineeringMechanics of Material010306 general physics021101 geological & geomatics engineeringSettore ICAR/07 - GeotecnicaSuction forceOedometer testMetastable sandPEGStabilizationCalcareniteSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiMechanics of MaterialsMechanical stabilitySoil waterNon polarMaterials Science (all)Settore GEO/05 - Geologia ApplicataGeology
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Stereocomplex Formation in Polylactide Multiarm Stars and Comb Copolymers with Linear and Hyperbranched Multifunctional PEG

2013

Poly ethylene glycolMaterials sciencePolymers and PlasticsOrganic ChemistryHyperbranched polymersPolymer chemistryPEG ratioMaterials ChemistryCopolymerPhysical and Theoretical ChemistryCondensed Matter PhysicsPoly(lactide)Ring-opening polymerizationMacromolecular Chemistry and Physics
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Multicompartment Micelles with Adjustable Poly(ethylene glycol) Shell for Efficient in Vivo Photodynamic Therapy

2014

We describe the preparation of well-defined multicompartment micelles from polybutadiene-block-poly(1-methyl-2-vinyl pyridinium methyl sulfate)-block-poly(methacrylic acid) (BVqMAA) triblock terpolymers and their use as advanced drug delivery systems for photodynamic therapy (PDT). A porphyrazine derivative was incorporated into the hydrophobic core during self-assembly and served as a model drug and fluorescent probe at the same time. The initial micellar corona is formed by negatively charged PMAA and could be gradually changed to poly(ethylene glycol) (PEG) in a controlled fashion through interpolyelectrolyte complex formation of PMAA with positively charged poly(ethylene glycol)-block-p…

Poly ethylene glycolMaterials sciencemedicine.medical_treatmentGeneral EngineeringGeneral Physics and AstronomyPhotodynamic therapyMicellePolyethylene Glycolschemistry.chemical_compoundInhibitory Concentration 50chemistryMethacrylic acidMicroscopy Electron TransmissionPhotochemotherapyIn vivoPolymer chemistryPEGylationmedicineGeneral Materials SciencePyridiniumMethyl SulfateMicellesACS nano
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Interactions between proteins and poly(ethylene-glycol) investigated using molecular dynamics simulations

2017

Poly(ethylene-glycol) (PEG) is a polymer used to coat therapeutic preparations, like drugs or drug nanocarriers, and improve their efficacy. This effect is probably due to a reduction of the interactions of the coated species with the host organism. Nevertheless, experiments show that PEGylated materials do interact with the surrounding biological milieu, and in particular with blood proteins. Here, we use atomistic molecular dynamics simulations to characterize the interactions between the polymer and several blood proteins. In these simulations, the proteins are immersed in a mixture of PEG and water molecules. We observe how PEG distributes around the protein surface and measure PEG-prot…

chemistry.chemical_classificationHistoryPoly ethylene glycoltechnology industry and agriculturemacromolecular substances02 engineering and technologyPolymer010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesBlood proteins0104 chemical sciencesComputer Science ApplicationsEducationMolecular dynamicschemistryHost organismPEG ratioBiophysicsMoleculeNanocarriers0210 nano-technologyJournal of Physics: Conference Series
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